The future of scientifically engineered bacterial weight-loss

The future of scientifically engineered bacterial weight-lossIn today’s world of Technology and Science, researchers and scientists alike are constantly conducting experiments to not only discover the common causes of diseases caused by unhealthy weight gain, but specifically how it can be chemically countered or more efficiently maintained.

Recent study demonstrating NAPE significance

Scientific researchers from the American Chemical Society (AMS) have recently engineered and have been testing a chemically engineered microbe in Mice (called NAPE) that promotes weight loss or otherwise prevents unnecessary or unhealthy weight gain. This is a naturally occurring compound in most human beings, but multiple illnesses and genetic makeups are responsible for the deprivation of such. Two groups of mice, one receiving the chemically engineered microbes, and the other without, were given the same high-fat diet but without the adding or reduction of chemicals in the intestinal track. The test yielded results demonstrating that mice that consumed the NAPE (through water as a compound) gained 15% less than the mice that did not.

The chemically engineered microbe that promotes communication to the brain of a sense of being full or otherwise promoting satiety was tested through these groups of mice at varying levels. The NAPE bacteria that was designed is to replace or strengthen current levels or absent level of the necessary bacteria to maintain a proper weight and diet.

Benefits of Gastric Bypass Surgery and physiological chemical components

Gastric Bypass Surgery was significant in increasing weight loss as it manipulated and removed specific gut bacterium and allowed for greater developmental processes and application of NAPE bacterium through the body to the brain.

In 2013, research was conducted through the Cedars-Sinai School of Medicine to determine which microorganisms were responsible for microbes called methanogens—compounded of methane—and how they were linked to obesity. The content of both this chemical natural compound in the body, as well as Hydrogen, were discovered to be interrelated through a study of 792 test-subjects in weight gain. The contents of said chemical compounds were recorded through breathalyzer-like scientific equipment. This research demonstrated that individuals with higher levels of each of these chemicals were more prone to have poorly performing intestinal processing and NAPE chemical relationships with the brain.

Taking into consideration the multitude of scientific variables related to gastric lining and operation, NAPE bacterial growth along with it’s connection to the brain leaves a lot of space for speculation and scientific justification between the intestinal system, the brain, and it’s relationship to weight loss.

Although mice have demonstrated in the past to be an effective animal to conduct experiments to obtain results relatable to how a human being might chemically or otherwise scientifically react, more extensive research much be conducted. Additionally, the approval of the Food and Drug Administration (FDA) would be required to test said microbes on humans. One concern to still be tested for example is how human beings on medications, special diets, fitness routines, or with compromised immune systems might react to the NAPE bacterial implant. Additionally, whether or not such a bacterium is contagious, and to what extent in order to prevent sharing it with others unwantedly.

Image credit: Alexander Raths

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