The future of scientifically engineered bacterial weight-loss

The future of scientifically engineered bacterial weight-lossIn today’s world of Technology and Science, researchers and scientists alike are constantly conducting experiments to not only discover the common causes of diseases caused by unhealthy weight gain, but specifically how it can be chemically countered or more efficiently maintained.

Recent study demonstrating NAPE significance

Scientific researchers from the American Chemical Society (AMS) have recently engineered and have been testing a chemically engineered microbe in Mice (called NAPE) that promotes weight loss or otherwise prevents unnecessary or unhealthy weight gain. This is a naturally occurring compound in most human beings, but multiple illnesses and genetic makeups are responsible for the deprivation of such. Two groups of mice, one receiving the chemically engineered microbes, and the other without, were given the same high-fat diet but without the adding or reduction of chemicals in the intestinal track. The test yielded results demonstrating that mice that consumed the NAPE (through water as a compound) gained 15% less than the mice that did not.

The chemically engineered microbe that promotes communication to the brain of a sense of being full or otherwise promoting satiety was tested through these groups of mice at varying levels. The NAPE bacteria that was designed is to replace or strengthen current levels or absent level of the necessary bacteria to maintain a proper weight and diet.

Benefits of Gastric Bypass Surgery and physiological chemical components

Gastric Bypass Surgery was significant in increasing weight loss as it manipulated and removed specific gut bacterium and allowed for greater developmental processes and application of NAPE bacterium through the body to the brain.

In 2013, research was conducted through the Cedars-Sinai School of Medicine to determine which microorganisms were responsible for microbes called methanogens—compounded of methane—and how they were linked to obesity. The content of both this chemical natural compound in the body, as well as Hydrogen, were discovered to be interrelated through a study of 792 test-subjects in weight gain. The contents of said chemical compounds were recorded through breathalyzer-like scientific equipment. This research demonstrated that individuals with higher levels of each of these chemicals were more prone to have poorly performing intestinal processing and NAPE chemical relationships with the brain.

Taking into consideration the multitude of scientific variables related to gastric lining and operation, NAPE bacterial growth along with it’s connection to the brain leaves a lot of space for speculation and scientific justification between the intestinal system, the brain, and it’s relationship to weight loss.

Although mice have demonstrated in the past to be an effective animal to conduct experiments to obtain results relatable to how a human being might chemically or otherwise scientifically react, more extensive research much be conducted. Additionally, the approval of the Food and Drug Administration (FDA) would be required to test said microbes on humans. One concern to still be tested for example is how human beings on medications, special diets, fitness routines, or with compromised immune systems might react to the NAPE bacterial implant. Additionally, whether or not such a bacterium is contagious, and to what extent in order to prevent sharing it with others unwantedly.

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Obesity in pregnancy leading to developmental disabilities

Obesity in pregnancy leading to developmental disabilitiesA recent study conducted by Laura Schieve–an epidemiologist with CDC’s National Center on Birth Defects and Developmental Disabilities—demonstrated that pregnant women who wewere considered overweight, per BMI standards, were much more likely to have children with development disabilities such as ADHD.

In addition to two recent previous  studies, the third most recent study consisted of 1,311 pregnant women, between the years 2005 and 2012. According to scientific research, a range of 18.5 to 25 is considered healthy according to BMI statistics. (A commonly utilized and trusted BMI calculator may be found here . This most recent experimental study was conducted on the pretext of altering and adding more sophisticated variables to further evaluate weight loss in these pregnant women, and the development of disorders in children such as Autism and ADHD. Any BMI that is 35 or more is considered to be obese in nature. This research experiment took into account added-weight from pregnancy, gestational diabetes, variations in diagnosis of postpartum depression, and even breast-feeding, along with it’s significance in nutritional effects and prospective weight loss.

These studies conducted to-date demonstrate that moms who are obese before and or during pregnancy are up to two times as likely to bare children who possess developmental disabilities, or psychological disorders that interfere with social development and academic learning among peers, per the DSM V (Diagnostic and Statistical Manual of Mental Disorders). The American Academy of Pediatrics found that mothers whom were overweight before and during pregnancy had at least a 3 times more likely chance of having a child that is born with autism spectrum disorder, and up to 4 times more likely to have developmental ADHD.

While obesity is already discouraged amongst men and women, there are specific advisories in place for women in which mention the inclination for women to be overweight more frequently than men, or suffer from a greater challenge to lose weight. There are numerous health risks associated with women that are brought on through overeating and obesity such as diabetes, high blood pressure, heart attack and even stroke. Additionally, overeating can lower mood, cause depression, a lack of motivation, and now also negatively impact their children.

Obesity and poor dieting during pregnancy can also lead to unhealthy lactation for a pregnant woman, and in turn (post-pregnancy) lead to further developmental health risks associated with their child. The lack of a proper diet during pregnancy can lead to malnutrition in a child and cause deprivation of much needed nutrients for brain growth, as well as subject a child to a stronger probability that he or she may develop other medical conditions such as diabetes. One theory listed by Schieve’s is that inflammation caused by poor dieting and obesity could contribute to improper growth of the brain of a child during and post-pregnancy.

In efforts to further understand a woman’s susceptibility for medical complications for both self and child, it’s strongly advised that a woman first visits the appropriate doctors to discuss risk, necessary changes, dietary, and fitness recommendations. While there are no guarantees with anything pertaining to Science, the statistical probability of otherwise developing additional or more complex physical or psychological disorders is more prevalent in mothers who have an abusive diet and unhealthy weight.

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Childhood Obesity and its relationship to Television

Childhood Obesity and its relationship to TelevisionIn today’s modern society in the United States, childhood and adolescent obesity is on the rise. Unfortunately, weight loss is on the decline. According to recent statistics by the Center for Disease Control and Prevention (CDC), in 2012 as many as one in every three children were considered to be obese or overweight.

Children who are viewing more than one hour of television per day will adapt to feeling less motivation and in turn hindering weight loss, while most likely an increased desire to watch more television. This behavior is unhealthy, as it takes away not only from social stimulation, but also cardiovascular and other important activities such as exercise.

In a Study conducted by The University of Virginia with over 11,000 children, tests demonstrated that this continued behavior (backed by statistical data from the CDC) demonstrate a doubling in nature of obesity and quadruple effect on adolescents as they increase their “TV time” across the nation.

Through taking into consideration statistical data collected by the Early Childhood Longitudinal Survey or CLS, information is demonstrated showing how school preparedness and cognitive development can be hindered through prolonged daily exposure to television by children and adolescents. Specifically, interfering with memory collection methods and application, as well as lowering motivation or amount of time committed to scholarly studies and social activities. This study was based off of the amount that these children watched television on a daily basis, and compared it to a representable similar technology: computers. While statistics were not collected and do not currently show similar side effects or intellectual deprivation, it is speculated that computer usage also can cause although much less, a measurable level of interference with social and academic commitments–as well as weight loss and management. Conversely, since it is less common to eat while using computers than watching television, we may appreciate why one form of technology is being attributed more strongly to weight gain than the other.

According to recent research conducted by Dr. Mark D. DeBoer, an associate professor in Pediatrics with the division of Pediatric Endocrinology at the University of Virginia, children can expect a 60% to 70% increase in weight gain and sustained overweight unhealthy study habits when exceeding 60 minutes per day of television. Per the American Academy of Pediatrics (AAP), the average kindergarten aged child watches at least three hours of television per day. The AAP recommends children watch no more than 2 hours per day, to promote more opportunity for weight loss—as DeBoer agrees. Depriving our children, society’s future, of physical and social activities indirectly or not is reprehensible and it is our job to educate fellow parents and interested parties alike of the associated risks. Some might argue that public education on the matter is not addressed enough. Additional research will be conducted by DeBoer to investigate further causes of childhood obesity associated with Television in the near future, as they take steps to collect longitudinal data representing short term to long-term effects in varying ages of youth.

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Chisel away at that beach body in new, more effective ways this summer!

Chisel away at that beach body in new, more effective ways this summer!For those of us who work 9-5 and have family, educational, and other commitments, working out can seem like a real impossible hassle.

From bodybuilders, coaches, sports athletes, to nutritionists, the message is all the more or less the same: focus more on diet, and less on time in the gym. The average American is overworking in the gym, not allotting enough time for recovery, and not aligning their workout routine with an appropriate dieting routine.

Consider the importance of disqualifying ‘vices’ from your life.

May it be that Hershey Bar once a day, bag of delicious Doritos with your sandwich (I’m guilty), that diet Pepsi, or Hershey Kisses (Sorry Hershey!) that you snack on throughout the day, consider the damage and both short term to long term negative impacts it has on your body and mind. Although Coffee alone may not seem like a total disturbance or diet pushback, consider the caloric and sugar contents involved with each coffee, and how many of those are fatty and will only contribute to more weight-gain and loss issues in the near future.

Disperse to burn those calories!

Eating 4-6 (smaller) meals throughout the day, if feasible, is most desirable in weight loss and control, as it promotes a healthier, more active metabolism. Additionally, this may very well increase the likelihood that you’re getting all of your much needed daily nutrition since you’re expanding on the various food-groups and meals you are consuming. Did you know that depriving yourself of foods, or even eating only 1-2 huge meals per day can have negative effects? Just think, your body will crave the nutrients and chemical compounds that you’ve deprived it of in the simplicity of such little meals, and in turn will only shoot over hunger pangs later on that will ultimately cause more weight gain. Weight loss is about dedication and commitment, but also remaining true and fair to your body through healthy measures. Anything that seems too easy, most likely is—and isn’t good for you either.

Baking at home v. ‘Caking’ at McDonald’s.

As opposed to easily consuming upwards of 1,400 calories just from eating out, consider the benefits of eating-in. Allow yourself, body, and mind to enjoy the lack of chemicals, quality of fresh meat or vegetables, and increase of nutrients through preparing and cooking your own food. Why settle for food for example vegetables that have such a broad array of chemicals in them and are months old (think: preservatives) when you can go to the Farmers Market or the likes and purchase fresh fruits and vegetables for so much less, on the dollar, and in greater quantity? Most people don’t realize it, but the quality of most TV Dinners match the quantity (poor, very tiny) and isn’t what’s really best for our bodies, though perhaps more convenient. Will you sacrifice your health and weight loss goals for ‘convenience? Just think, eating out and even at home, just two rolls with regular butter can easily equal up to 500 calories! For those of us that are ‘bulking’ that’s great, but for the rest who are cutting or aimed at weight loss, this is not good or recommended.

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Does More Fat Equil Less Fat?

Does More fat equil Less fat?A lot of people from all walks of like on a regular basis—including myself—may or may not at some point or another get caught up in the newest weight loss trend, or muscle-gaining techniques. In example, Acai Berries as a ‘wonder vitamin’ or drug to weight loss.

For some reason in the recent past, eating fatter to lose fat has been a growing ‘trend’. However, recent studies by an associate professor Matt Hulver at Virginia Tech and lead author recently published the significance of fat increase, counter weight loss, and the dangers of fat to our muscles and bodily functions.

With a fatter diet, easily comes more muscle restriction. It’s so important for our muscles to operate properly, not only to look ‘sexy’ but also to serve the purpose of transferring blood, sugars, salts, and proteins.

Adding 55% fat to your diet, ‘good’ or ‘bad’, will still most commonly have negative impact on any weight loss attempts. That is, because too much of any fat is not good for the body, and is unnecessary. More so, we should concentrate on important nutrients, such as proteins, calcium, other vitamins, and appropriate levels of sodium and glucose—not found well balanced in most fats, especially unhealthy ones as they are loaded.

Consider positively contributing to your metabolism processing, along with your workout routine related aspirations for weight loss. A recent publishing in the Biological Psychiatry shows that simply after one high-fat meal, your metabolism and body can begin to slow, and break down in muscle operations. This can even cause high blood pressure, and ultimately a heart attack as essential operations within the body to regulate chemicals, burn and utilize fat appropriately, and allocate sugar and salts suffer from undue interference.

With added-fat in your diet you will not only interfere and negatively impact your metabolism, sugar and salt levels, but also your mind. Diets high in unhealthy fats (and fats in general) can cause fatigue, laziness, lack of motivation, and even depression. While eating those 20 chicken wings may initially feel great and give us a mood boost, we may ultimately suffer than succeed in our object by having remorse for eating the unhealthy food, and also negatively impacting our already poor or less than desirable diet. While eating more healthy vegetables, meats, and carbs can positively contribute to our diet, it’s important to conduct research to study and learn the difference between what ‘good’ and ‘bad’ carbs are, and the same rules would apply for fat. Like anything in the realm of nutrition, what we consume can only be so beneficial within reasonable portions, and over intake of anything can be bad for the mind and body towards weight loss, and general health and wellness.

Avoid gaining up to an extra 11 lbs per year by reducing to remove unnecessary, unhealthy fats from your diet. Consider the value, and most realistic substitutes for your current sugar, salt, and fatty basic foods, groups, and unhealthy habits.

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The Weight Loss: To Go Beyond Diet Changes And Exercise

The Weight Loss: To Go Beyond Diet Changes And ExerciseAccording to some researchers, the doctors should go beyond advising obesity patients to exercise more and eat less for weight loss. They should aim on their biological mechanisms which makes it difficult for these people to reduce weight, say researchers. Pediatrics and psychiatry professor Ochner points out that whenever people diet, various biological mechanisms take place within the body.  The body feels it is starving which encourages the person to have more food. To conserve the fats, the body begins to slow down the calorie burning rate and changes inside brain attract people to calorie rich food, says Ochner.

The medicine school professor from New York further explains the matter. According to him, such mechanisms evolved in order to help humans in surviving scare availability of food. However, the problem lies in the fact that similar mechanism operates in case of people weighing 400lbs and looking to reduce 40 lbs. It is enough to explain the reason why obese people after weight loss regain weight. As per Ochner, people that are obese for several years tend to be stamped biologically in terms of their bodyweight.

Ochner believes that more attention to be paid in biological treatments for the obesity, like surgery and drugs. The doctors should have the awareness that offering advice to exercise and check diet may be insufficient for the obese people. However, the recent biological treatments to cure obesity are quite expensive. The reliable data on long term effectiveness of new drug treatments are also lacking. Bariatric surgery or weight loss surgery involves an operation of intestine and stomach. It has been the only obesity treatment which has produced long term results for people. There aren’t enough ways to treat obesity as per its biological mechanism. One should find out safer and wide available means, says Ochner.

In a medical journal, Ochner and his colleagues have recommended lifestyle modification for the treatment of individual suffering sustained obesity. However, this should be a single component of the strategy of multimodal treatment. Doctors should consider the positives and negatives associated with biological treatments. According to researchers, they would weight these factors against a patient’s obesity based disorder risks.

Medical school profession Cohen emphasizes that importance of understanding the biological process behind weight loss. According to Dr. Cohen, human history says it was either unavailability of food or illnesses which lead to losing weight. Human body consists of standard biological mechanisms which maintains the weight, believes the assistant professor from Harvard Medicine School. However, he refrains from prescribing drugs for weight loss to all his patients owing to insufficient data confirming their long term benefits and safety.

According to Cohen, obesity possesses a risk element for the future health issues but it isn’t a disease. It requires to be treated as per risks associated for future problems out of it. Most of the experts are unanimous that doctor’s focus should be preventing obesity as lifestyle changes are quite effective with overweight and not overweight people, said Ochner.

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Ways to Keep The Weight In Check

Ways to Keep The Weight In CheckThe desire for weight loss is there with overweight people irrespective of gender. It is not an easy thing to cut down on weight. However, the following methods will guide you into the right direction:

Begin with strength training

Even at rest, your muscles burn more calories than the fats. Pursue strength training for at least twice or thrice a week. It works in your favor by improving your strength, expressed Jim White, a registered dietician and personal trainer.

Stay away from tempting foods

According to author Cynthia Sass, people in general are attracted to foods which are easy to reach. So store them at a location which is strenuous to reach for weight loss practice. Foods like fresh fruits and popcorn should be more visible and placed at arm’s length. Have a water bottle to avoid searching for water in the refrigerator or somewhere else.

Make a note

People tend to overestimate their state of activeness and underestimate their food consumption levels. According to some studies, making a note of everyday consumption could double the targeted weight loss. Putting down everything on writing for even a short while is the right way to remain mindful.

Personalize the food portions

Women who consume food in the company of a man should customize their portions as per bodily needs. It might involve including extra veggies and minimizing on protein rich and fat foods.

Get rid of irresponsible eating habits

According to author Pamela Peeke, it is important to check the reason of your food craving. She has written a book which deals with recovering from food addiction and overeating. She advises to be aware of inner emotions to find out the reasons for abnormal cravings.

Get a good sleep

To help your weight loss efforts, it is important to have a sleep of seven or eight hours regularly at night. Never compromise on sleep and don’t ever go below six hours. Failing to do so would activate the hunger hormones and appetite. It will steer out of control and make you vulnerable to overeating.

Practice meditation regularly

Author Peeke says that it is significant to be aware of your inner feelings and adapt to stress. Indulging oneself in some kind of introspective activity on a daily basis should be more than handy.

Make plans for the future

Whenever you are out of home, make sure that you are packing the food by yourself. As result, you won’t be vulnerable to end up eating unhealthy foods or oversized portions. Thus, planning ahead will be more often helpful in your weight loss efforts.

Keep your hunger in check

Make sure that you are eating after three or four hours of break. However, if you are feeling hungrier, you may be prone to all cues and triggers which causes overeating, believes food writer Peeke.

Avoid sitting idle through the day

Make sure that you are not staying sedentary throughout the day. Even the activities which are moderate in intensity would be helpful. For instance, walking helps to rein in appetite and keeps you energized.

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Unfortunate rise in obesity and inactivity in the US states

Unfortunate rise in obesity and inactivity in the US statesHawaii stands as the fittest state while the Americans in total are less active and more obese. It is revealed by annual Health Rankings of America in its new findings. The health of this nation in both short and long term basis including the highs & lows for last 25 years came out in state-wise analysis. It was reported by MNT and the report came out in UHF. This same report was also published in Partnership for Prevention and America’s Public Health Association.

For third time in a row, Hawaii emerged as the fittest state. It was followed by the states of Vermont and Massachusetts. It was Mississippi that stood as the lowest healthy state for third time consecutively. Arkansas came second as the lowest healthy state while Louisiana came third in the year’s report.

Hawaii’s ranking owes it to factors like lower prevalence in obesity and smoking. There are also lower rates of child poverty and preventable hospitalizations. Cardiovascular deaths and cancer deaths have also dropped down. Mississippi is facing challenges that include higher rates of child poverty, diabetes, physical inactivity, obesity, etc. It is also stuck with minimal availability for primary care physicians.

In totality, the rate of obesity in America stands at 29.4 % in the adults in 2014 from the 27.6 a year back. It is a jump of 153 % from 1990 figures. Life expectancy has recorded a historical high at 78.8 yrs. It ranks 34th all over the world and there was a rise in the chronic conditions for the last 25 years. Several of these are preventable which compromises the standard of life. The short term successes came in form of 3% drop in smoking prevalence among Americans. Infant mortality rate has dropped and immunization coverage has soared by five percent. On the other hand, there is 7% increase in drug deaths and obesity while physical inactivity has moved up by 3%.

The same report indicated successes and the challenges in long term. During the last 25 years, the smoking prevalence dropped by 36% and air pollutions levels have also come down. Infant mortality rate fell down by 42% while cardiovascular and cancer deaths reduced by 38% and 4% respectively. The study traced that from 1990; only eight of the challenges have been unchanged or deteriorated. There is 153 % rise in obesity and there is also an upward climb in physical inactivity and diabetes rate However, the date obtained after the past three years display a leveling of this prevalence.

According to Anna Schenck of Health Rankings Committee, the healt outcomes in US are worse compared to some developed countries. This is the scene despite exhausting a bigger percentage of economic resources in the field of health care compared to others. She said that it is the right time and opportunity to bring improvements on health by focusing on prevention. She also asserted that this kind of opportunity knocks the door just once in an entire generation.

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Weight loss rate has little relevance to successful maintenance of weight

Weight loss rate has little relevance to successful maintenance of weightIn a study of the weight loss rate, researchers found that the time taken by people to lose weight does not have any significant influence on the successful maintenance of the new weight. The participants were studied over a span of 3 years, during which they regained certain percentage of the lost weight irrespective of how long they took to lose it. The study was carried out by a team of researchers from Australia, and the lead author of the report was Joseph Proietto.

The researchers say that the study reveals the need for the revision of the current guidelines that advise slow weight loss for sustainable result. Instead, improvement of the methods for maintenance of weight-loss has to be the focus. Obesity or overweight is perceived as a behavioral issue by many, and the belief that steady and gradual achievement of weight-loss is more sustainable seems to have originated from that perception. Indeed, habits change slowly and the more graduated the process is the greater it sustainability is. However, obesity is caused not just because of inappropriate lifestyle, it is significantly genetic too.

Scientific evidence does not back the claim that slow weight loss makes maintenance of weight more sustainable, according to Proietto. Irrespective of how the weight is lost, individuals generally have difficulty in maintaining the new weight as many of them regain much of it.

A trial was chalked out by Proietto to test the influence of the weight-loss rate on sustainability. The study was divided into 2 parts – weight loss and weight maintenance. There were 2 weight-loss programs – rapid and gradual. The study was carried out on two hundred obese adults equally divided into the 2 weight-loss programs. The 1st part lasted for 36 weeks. In the 2nd phase of the research, the participants were provided with individualized diet plans and instructed to consult a dietician after every twelve weeks.

The researchers found that 81% of the participants, who were on the quick weight-loss program, achieved the target-weight in comparison to only 50% of their counterparts. In the 2nd phase of the research, most of the participants from both the groups regained around 71% of the lost weight. Thus, it was concluded that the time required to lose weight had no significant influence on the maintenance of the new weight.

The study made some other significant revelations. Only about 15% of the people may actually be able to lose their weight as well as maintain it with the help of exercise and diet. The exercise that is needed to maintain the weight post weight loss is extremely tough to be incorporated into the contemporary lifestyle. Pharmacotherapy may be a considerable option for those who are regaining weight despite rigorous effort. However, there is no strong evidence to establish that pharmacotherapy does offer sustainable success. The weight-loss rate did not affect appetite and hunger of the participants either.

Proietto said that appetite suppression may be considered after successful achievement of weight-loss, none of the many effective medicines have been properly tested.

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Study reveals that breakfast may not be that significant for weight loss

Study reveals that breakfast may not be that significant for weight lossBreakfast has always been known to be the most significant meal of the day. Breakfast revives metabolism and provides early nutrition which plays a significant role in sustaining the human-body through the day. It also prevents people from overeating at lunch, having a partial lunch earlier and then another semi-meal later in the afternoon, etc. Therefore, having breakfast has always been described a very important towards weight loss. However, a new research that has been published in an American journal on clinical nutrition has raised considerable questions on the belief. The research revealed that the success for those who had breakfast in the morning was virtually the same as that for those who did not.

Why breakfast has the credit?

Research carried out earlier have always focused on the possibility of being obese or overweight among those who missed breakfast. However, there has hardly been any study that proved it to a substantial cause for weight-gain. The misinterpretation of correlation as causation was pointed out by Emily Dhurandhar, who is the Assistant Professor of Health Behavior at The University of Alabama in Birmingham and was the lead author of the research. However, Michelle Cardel, the co-author, notes that breakfast may not have much significant role in weight loss, it is still important otherwise.

The Study

The research was carried out on 309 people, divided into 3 groups. All the 3 groups were given the same USDA pamphlets that described nutritious habits. The pamphlets of 1st group had no mention of breakfast while that of the 2nd group additionally instructed to have breakfast before 10 o’clock in the morning, and the 3rd group was told not to have anything solid until 11 o’clock in the morning. The groups were observed for 112 days, after which the conclusion was derived.

The Result

The study was completed by 283 participants, who accomplished the same average weight loss. Thus, breakfast was found to have no crucial effect on weight loss of the volunteers. The result also highlights the need for evidence along with the beliefs that prevail regarding nutrition today.

Limitations to the Study

According to Cardel, the study was not free of limitations. First, the volunteers had the liberty to choose the food-items that they wanted to have for breakfast. So, there is no conclusion on the quantity and type of food that people. It cannot be said whether prescribing the type and amount of food for breakfast could have yielded different result. The study did not take into account the appetite of the participants. So, it is not known who ate how at breakfast and other meals. Thirdly, the study spanned a period of only 112 days, which might be too small a time to observe the nutritional effect of breakfast in weight loss.


Although the research had limitations, it signified at the need for evidence in support of the claims that are widespread in the world today. The study has not diminished the significance of breakfast as the first meal of a day but revealed that it is not crucial towards losing weight.

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